SpaceX's CRS-27 mission delivered food, equipment, and experiments to the ISS on Tuesday.
The Kennedy Space Center in Florida launched the Dragon spacecraft on time.
Five minutes into flight, SpaceX reported seeing the second stage engine ignite from the ground.
On Monday night, SpaceX tweeted 50% favourable weather for Tuesday's launch window, then 80%.
Normal launch stages. Falcon 9 landed on Shortfall of Gravitas eight minutes after launch.
The Falcon 9 booster completed its mission after Cargo Dragon reached its planned orbit.
Spaceflight Now says that the commercial resupply mission will deliver 6,300 pounds of food.
SpaceX's 27th Dragon spacecraft mission for commercial resupply services was Tuesday's.
SpaceX tweeted that recovery will be done by women. It claims to be the first all-female crew.