NASA-SpaceX Crew-5 mission concludes with astronauts returning from launch in October 2022.
Crew-5 will undock from ISS, come home in SpaceX's Dragon capsule, and splash down off Florida.
A few hours before their departure from the ISS, Crew 5 offers their gratitude to the ground crew.
She praised Crew-5 for five months of training and challenges.
ISS cosmonauts and astronauts' mission was prolonged by a year due to a Soyuz leak.
Crew-5 spent a week with Crew-6 after welcoming them to the ISS on Friday, March 3. (NASA)
Crew-5's over 200 research and technology experiments on the ISS.
Lunar rovers and fuel tanks undergo liquid behaviour testing in virtual lunar gravity.
They also grew space tomatoes so ISS and deep-space explorers can cultivate their own food.